Antioxidant effects of natural bioactive compounds.
نویسندگان
چکیده
Reactive oxygen species (ROS), as well as reactive nitrogen species (RNS) play either harmful or beneficial role in biological systems. Beneficial effects of ROS include physiological roles in cellular responses against infectious agents and in several cellular signalling pathways. Harmful effects are due to high concentrations of ROS, which can damage biomolecules, including lipids, proteins and nucleic acids. The harmful effects of ROS are counterbalanced by the antioxidant action of both antioxidant enzymes and non-enzymatic antioxidants; however, despite the presence of the cell's antioxidant system, oxidative damage accumulates during the life cycle and has been proposed to play a pivotal role in the development of age-dependent diseases such as atherosclerosis, arthritis, neurodegenerative disorders and cancer. Numerous epidemiological studies indicate that a reduced risk of various lifestyle diseases, mainly cardiovascular diseases and cancer, as well as other disorders, is associated to a diet rich in fruits, vegetables and their products. The drive to enhance the consumption of fruits and vegetables in the human diet is linked with positive effects of beneficial antioxidants impacting on health promotion. In this review we present an outline of main roles of ROS in biological processes and diseases and how natural bioactive compounds of fruits and vegetables determine their health-promoting properties.
منابع مشابه
Seasonal effects on bioactive compounds and antioxidant capacity of six economically important brassica vegetables.
Research on natural and bioactive compounds is increasingly focused on their effects on human health, but there are unexpectedly few studies evaluating the relationship between climate and natural antioxidants. The aim of this study was analyze the biological role of six different Brassica vegetables (Brassica oleracea L. and Brassica rapa L.) as a natural source of antioxidant compounds. The a...
متن کاملExtraction of Phenolic Compounds from Black Mulberry Using Aqueous, Ethanol and Aqueous-Ethanol Solvents: Effects of Heat Treatments on Chemical Properties of the Extracts
Background and Objectives: Black mulberry is a juicy and dark purple to black fruit with a good balance of sweetness and tartness. This fruit is highly interested due to high quantities of anthocyanins. The bioactive compounds are often present in fruit tissues and should be released. The aim of this study was to extract bioactive compounds of black mulberries and assessment of heating process ...
متن کاملBioactive compounds from natural product extracts in Taiwan cosmeceuticals-Mini review
Botanicals (herbal materials and extracts) are primarily added to the formulations due to different related properties such as antioxidant, anti inflammatory, antiseptic and antimicrobial effects. The bioactive compounds from natural product extracts have been successfully utilized in various applications of the skin care. The bioactive compound from natural product extracts does not possess an...
متن کاملAntioxidant compounds with antioxidant properties in seaweed and their application in various industries
Marine algae are known to contain a wide variety of antioxidant compounds. Natural antioxidants, found in many algae, are important bioactive compounds that play an important role against various diseases and ageing processes through protection of cells from oxidative damage. There is now a global interest in finding new and safe antioxidants from natural sources. Algae can have a variety of pr...
متن کاملChemical composition and antioxidant properties of some species of Lamiaceae family from Iran
Spearmint (Mentha spicata L.), oregano (Origanum vulgare L.) and thyme (Thymus vulgaris L.) are used as traditional medicines, culinary herbs and food flavorings. All samples collected from Khuzestan province, Iran and plant extracts prepared using Clevenger apparatus. Antioxidant capacity and major parameters affecting antioxidant properties including total phenolics, flavonoids and vitamin C ...
متن کاملIsolation and evaluation of cytotoxic and antioxidant activity of bioactive metabolites of cultured actinobacteria in Persian Gulf marine sediments
Screening bacteria for bioactive compounds is the first step in the drug discovery programs. The aim of the present research was to achieve cytotoxic and antioxidant metabolites from actinobacteria of Persian Gulf sediments and to investigate the effects of combinations of seven treatments and six isolation media on the selective isolation process. A total of 395 actinobacterial isolates were c...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Current pharmaceutical design
دوره 15 26 شماره
صفحات -
تاریخ انتشار 2009